凝-花色素水凝生物,抗菌和机械性能用于牙科应用
Andrea Itzamantul Flores-Espinoza1, Rene Garcia-Contreras1, Dulce Araceli Guzman-Rocha1
1Interdisciplinary Research Laboratory (LII), Nanostructures and Biomaterials Area, National School of Higher Studies (ENES), Leon Unit, National Autonomous University of Mexico (UNAM), Leon 37689, Mexico.
Biomimetics (Basel, Switzerland)
|December 22, 2023
概括
新的凝-奇托桑水凝在牙科伤口护理方面显示出有前途的结果. 它们表现出良好的降解,胀和机械强度,具有显著的抗菌活性和干细胞兼容性.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料 牙科材料
- 组织工程是组织工程.
背景情况:
- 奇托是一种天然的多糖,用于水凝中治疗伤口的应用.
- 评估基托基材料的细胞毒性和抗菌性质对于牙科应用至关重要.
研究的目的:
- 为了评估机械特性,抗菌活性对Streptococcus mutans,和生物效应的凝 - 基托桑水凝与从角膜 (SCAPs) 的干细胞.
主要方法:
- 在不同度 (0%,0.2%,0.5%) 的合成凝-奇托桑水凝.
- 评估了降解,膨胀能力和机械性能 (UTS).
- 评估了SCAP相互作用 (通过MTT测定粘附,扩散) 和对S. mutans的抗菌作用 (agar扩散,微稀释).
主要成果:
- 水凝显示有控制的降解和显著的膨胀能力.
- 福利埃变换红外光谱学证实了水凝的功能组.
- 证明了对SCAP增殖的剂量依赖性影响,并显著降低了S. mutans的生存能力.
- 素的存在增强了机械性能 (UTS).
结论:
- 凝-基托桑水凝具有有利的降解,胀和机械性能.
- 水凝对S. mutans表现出显著的抗菌活性,并支持SCAP增殖,具有轻微的细胞毒性.
- 这些发现表明,凝-奇托桑水凝在术后牙科护理敷料中的潜在应用.
相关概念视频
Waterproofing and Anti-Bacterial Admixtures in Concrete
Concrete's susceptibility to water absorption is due to the capillary action within the pores of its hydrated cement paste. This action draws water in, creating the need for waterproofing admixtures to prevent such penetration. The efficacy of these admixtures is contingent upon the water pressure, with variations arising from different conditions such as rain, capillary rise, or hydrostatic pressure in structures intended to hold water.
Waterproofing admixtures render concrete hydrophobic,...
Waterproofing admixtures render concrete hydrophobic,...
Special Staining Techniques
Specialized staining techniques play a vital role in microbiology by enabling the visualization of specific bacterial structures that remain undetectable with standard microscopy methods. These techniques not only enhance the structural visualization of bacterial cells but also provide critical insights into their pathogenicity and classification. Additionally, they support diagnostic and research endeavors in microbiology by identifying key bacterial features.Capsule Staining for Virulence...
Chemical Agents for Microbial Control
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...


