甲基菌素的分类学分布和分子进化
Marco Gerdol1, Daniela Eugenia Nerelli1, Nicola Martelossi1
1Department of Life Sciences, University of Trieste, Via Licio Giorgieri 5, 34127 Trieste, Italy.
Marine drugs
|December 22, 2023
概括
甲基菌素,R型菌素的一个子组,显示出古老的进化起源和广泛的分类分布. 大多数具有独特的嵌合体结构,这表明二级域损失在更简单的形式.
科学领域:
- 进化生物学是进化的生物学.
- 生物化学 生化学
- 分子生物学分子生物学
背景情况:
- R型莱克是无处不在的糖结合蛋白质,具有特有的β-三叶子折叠.
- 甲基菌素,这些菌素的子组,已经显示出生物技术应用的潜力.
- 之前的研究已经在贝中发现了菌素和足动物中的相关序列,这表明了基因家族.
结论:
- 这些发现揭示了古老的进化根源和广泛的,斑点分布的mytilectins.
- 常见的模拟结构表明,更简单的甲基菌素结构可能是二级域损失的结果.
- 这项研究为了解菌素进化和潜在应用奠定了基础.
更多相关视频
相关概念视频
Evolutionary Relationships through Genome Comparisons
5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Phylogeny
44.2K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
44.2K
Gene Evolution - Fast or Slow?
7.1K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.1K
Cis-regulatory Sequences
9.9K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
9.9K
Convergent Evolution
27.8K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
27.8K
Overview of Myosin Structure and Function
4.3K
Myosins are a family of molecular motor proteins, first identified in the skeletal muscles, where they are responsible for muscle contraction. Along with their role in muscle contraction, these proteins also play a role in the intracellular transport of molecules and vesicles. There are twenty-four classes of myosins based on their domain sequence and organization. Of the twenty-four, six classes (Myosin I, Myosin II, Myosin V, Myosin VI, Myosin VII, and Myosin X) have been well...
4.3K


