亲密伴侣暴力和坚持PrEP和ART在乌干达艾滋病毒血清不同的夫妇中
Dorothy Thomas1, Lylianne Nakabugo2, Florence Nambi2
1Department of Global Health, University of Washington, Seattle, WA.
Journal of acquired immune deficiency syndromes (1999)
|December 22, 2023
概括
亲密伴侣暴力对抗逆转录病毒治疗 (ART) 的坚持有负面影响. 关系的力量影响了艾滋病毒病毒不同夫妇的暴露前预防 (PrEP) 坚持. 这些发现强调了解决艾滋病毒护理中的关系动态的重要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 亲密伴侣暴力 (IPV) 增加了艾滋病毒的风险,并减少了艾滋病毒护理的参与.
- 关于IPV和关系动态如何影响HIV与血清不同伙伴关系中的抗逆转录病毒治疗 (ART) 和暴露前预防 (PrEP) 的坚持存在有限的理解.
研究的目的:
- 在乌干达的血清不同的夫妇中评估IPV暴露和ART/PrEP坚持之间的关联.
- 评估关系力量动态与ART/PrEP坚持之间的关系.
主要方法:
- 使用了双项通用线性混合效应回归模型.
- 149名异性恋艾滋病毒血清异性伴侣被纳入并进行了跟踪.
- 两个伴侣都被评估IPV暴露,关系无能,以及ART/PrEP坚持.
主要成果:
- IPV暴露与较低的ART坚持相关 (OR:4.78,95%CI:1.48-15.42).
- 在IPV暴露和PREP坚持之间没有发现显著的关联 (P=0.69).
- 关系无能与艾滋病毒阴性个体 (OR:0.57,95%CI:0.36-0.90) 中更好的PrEP坚持有关.
结论:
- 暴露于IPV与减少ART坚持有关.
- 关系的力量动态影响了prep的坚持.
- 调查结果强调了IPV和关系力量对不同血清联盟的ART/PrEP坚持的影响.
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