对直立姿势的心率反应的差异与心率波动的高频功率的变化有关
Heidi Bouquin1, Jenni K Koskela1,2, Antti Tikkakoski1,3
1Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
American journal of physiology. Heart and circulatory physiology
|December 22, 2023
概括
从躺到站时心率的增加是心血管健康的可靠指标. 这种反应在个体之间有很大差异,反映了自主神经系统调节和血管功能方面的差异.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统功能 自主神经系统功能
- 血液动力学 血液动力学
背景情况:
- 高静止心率是已知的心血管风险因素.
- 有限的数据存在于血液动力学和心率从卧式到直立的增加的可重现性.
- 了解这种生理反应对于评估心血管风险至关重要.
研究的目的:
- 为了研究心率从仰卧姿势增加到直立姿势的血液动力学特征和可重现性.
- 为了探索心率变化 (HRV) 与卧卧直立心率变化之间的关系.
- 确定卧卧直立心率的增加是否是一种可重现的生理现象型.
主要方法:
- 在574名志愿者中,在被动的头向上倾斜 (HUT) 期间,使用阻抗心脏图和度计记录了非侵入性血液动力学.
- 进行心率变化 (HRV) 分析以评估自主调节.
- 在215名参与者中,在多次HUT会议中评估了可重复性.
主要成果:
- 从仰卧到直立的心率的增加在四分位数 (4.7到21.0次/分钟) 中有显著的变化.
- 较高的心率增加与较低的直立高频HRV (表明较少的副交感调制) 和较低的全身血管阻力有关.
- 心率从俯卧到直立的增加是高度可重现的 (r = 0.682).
结论:
- 俯卧至直立心率的增加是一种可重现的血液动力学表型.
- 这种表型与心脏副交感声调节和全身血管抵抗的独特模式有关.
- 仅仅是休息心率不足以根据心血管功能差异对个人进行分类.
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