用贝利马布治疗的系统性狼患者的COVID-19:一项回顾性临床研究
Yinlan Wu1,2,3, Yanhong Li1,2,3, Tong Wu1,2,3
1Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China.
Immunologic research
|December 22, 2023
概括
在全身性红斑狼 (SLE) 患者中,贝利马布治疗没有增加COVID-19风险. 这种疗法可能有助于缓解SLE患者的冠状病毒病2019症状.
科学领域:
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 接受免疫抑制剂的全身性红斑狼 (SLE) 患者面临SARS-CoV-2感染的风险增加.
- 贝利马布是一种SLE治疗方法,对COVID-19的结果有未知的影响.
- 这项研究探讨了贝利穆马布对SLE患者COVID-19的影响.
研究的目的:
- 为了研究贝利穆马布对SLE患者COVID-19症状的影响.
- 评估贝利穆马布在SLE患者的SARS-CoV-2感染期间的安全性和有效性.
主要方法:
- 招募了123名接受贝利马布治疗的SLE患者.
- 通过电话跟踪收集了患者和同居者的COVID-19数据.
- 对COVID-19症状和药物使用进行了比较,以评估贝利穆马布的影响.
主要成果:
- 89.4%的SLE患者的SARS-CoV-2检测结果呈阳性.
- 接受贝利马布治疗的患者比同居者表现出较少的COVID-19症状 (p < 0.001).
- 停止使用贝利马布并没有增加因SARS-CoV-2感染而入院的风险.
结论:
- 贝利穆马布治疗不会增加对COVID-19的易感性.
- 贝利马布在SLE患者中有益地减轻COVID-19症状.
关键词:
贝利穆巴姆的情况是这样的:冠状病毒疾病2019年 (COVID-19) 是一个疾病.追溯性临床研究 追溯性临床研究严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)系统性红斑狼 (SLE) 是一种更多相关视频
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