随着免疫检查点抑制剂与尼沃卢马布和伊皮利穆马布联合治疗诱导的糖尿病酸性症后,闪发光的ACTH降低:一个病例报告
Hiroshi Iesaka1, Hiraku Kameda1, Aika Miya1
1Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Medicine
|December 22, 2023
概括
免疫检查点抑制剂 (ICI) 可以导致缺血炎,一种严重的免疫相关不良事件 (irAE). 这一案例突出显示,在接受尼沃卢马布和伊皮利穆马布治疗的患者中,ACTH缺乏和二次上腺功能不全的迅速发作.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
背景情况:
- 免疫检查点抑制剂 (ICI) 越来越多地用于癌症治疗.
- 与免疫相关的不良事件 (irAEs) 是ICI的常见副作用.
- 低体炎是一种严重的irAE,可以导致二次上腺功能不充分.
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