埃塞俄比亚第三级医院外科病房的抗菌素使用相关问题和决定因素
Yirga Legesse Niriayo1, Melisew Ayalneh1, Gebre Teklemariam Demoz2
1Department of Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia.
PloS one
|December 22, 2023
概括
与抗生素使用相关的问题在住院外科手术患者中很常见,影响60%以上. 关键问题包括需要额外的药物,不必要的处方和不正确的剂量,突出了改善抗菌药物管理的领域.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 与抗生素相关的问题有助于耐药性,治疗失败和医疗费用增加.
- 关于住院外科病人的抗微生物药物使用问题存在有限的数据,特别是在特定的医疗机构.
研究的目的:
- 调查在医院环境中手术患者中使用抗生素相关问题的流行率和决定因素.
- 确定特定类型的抗生素相关问题和相关的风险因素.
主要方法:
- 在北埃塞俄比亚的一个外科病房进行的一项前性观察研究.
- 通过患者访谈和医疗记录审查收集的数据,根据既定指南评估抗生素的适当性.
- 使用Cipolle的方法和专家共识确定了与抗生素使用有关的问题;用于找到决定因素的后勤回归.
主要成果:
- 在272名手术患者中,超过61%的患者经历了与抗生素使用相关的问题,发现了235个问题.
- 常见的问题包括需要额外的药物治疗 (29.4%),不必要的药物治疗 (15%) 和错误的剂量 (12.1%).
- 素,青素和甲尼达是涉及最多的抗生素类别; 长时间住院,多药 (≥5种药物) 和较低的从业者资格预测了这些问题.
结论:
- 与抗生素使用相关的问题在住院的外科手术患者中很普遍.
- 长时间住院,多药店和缺乏经验的从业者是重要的预测因素.
- 干预措施应专注于高风险患者,并加强合格专家在患者护理中的参与.
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