与 Chikungunya 急性阶段住院相关的因素
Danielle Torres Dos Santos Lopes1, Crispim Cerutti Junior1,2, Aline Areias Cabidelle3
1Postgraduate Program in Infectious Disease, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
PloS one
|December 22, 2023
概括
奇孔古尼亚热病的住院治疗并不常见,但影响年轻人和老年人,以及孕妇. 某些症状,如背部疼痛,可能表明住院的风险较低.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 奇孔古尼亚病毒 (CHIKV) 感染可能导致严重的疾病,需要住院治疗.
- 识别严重的奇孔古尼亚风险因素对于资源配置和患者管理至关重要.
研究的目的:
- 为了确定与 Chikungunya 急性阶段住院相关的人口和临床特征.
- 为了确定与 Chikungunya 相关的住院治疗的风险因素和保护因素.
主要方法:
- 这是一项横截面研究,分析了巴西维托里亚 (Vitória, Espírito Santo) 报告的2868例奇孔尼亚病例 (2016年3月 - 2021年12月) 的数据.
- 统计分析用于比较住院和非住院患者之间的特征.
主要成果:
- 住院治疗发生在1.42%的病例中 (n=41).
- 住院患者的年龄较小 (P < 0.001) 和更频繁的怀孕 (P = 0.010).
- 两岁以下和65岁以上的个人占住院病例的31.7%. 背部疼痛 (OR=0.134) 和关节痛 (OR=0.226) 与较低的住院风险有关.
结论:
- 幼儿和老年人患小孔古尼亚病的风险更高,即使症状不那么严重.
- 怀孕是急性 Chikungunya 住院的危险因素.
- 需要进一步研究在高危人群中管理严重的奇昆古尼亚.
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