在儿童和青少年肺栓塞的长期结果
Denise Bastas1, Leonardo R Brandão1,2, Jennifer Vincelli2
1Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.
Blood
|December 22, 2023
概括
儿童肺栓塞 (PE) 的长期后果是显著的,许多儿童经历功能障碍. 潜在的疾病会增加风险,强调需要促进PE后的体育活动.
科学领域:
- 儿科肺病学 儿科肺病学
- 心血管研究研究心血管研究
- 临床结果 临床结果
背景情况:
- 关于肺栓塞 (PE) 在儿童群体的长期影响的知识有限.
- 了解这些结果对于制定有效的后续协议至关重要.
研究的目的:
- 描述儿科肺栓塞 (PE) 的长期结果.
- 为了比较患有和没有潜在疾病的儿童之间的结果.
- 确定影响PE后功能恢复的因素.
主要方法:
- 一项队列研究跟踪了150名被诊断患有PE的儿童 (0-18岁) 至少6个月.
- 随访包括临床评估,成像,心声学,肺功能测试和心肺运动测试.
- 评估的结果是PE解决,复发,死亡和功能障碍.
主要成果:
- 肺栓塞 (PE) 在71%的儿童中消失;9%的儿童出现复发,5%的儿童死亡.
- 三分之一的人有过渡性功能障碍,包括呼吸系统问题 (31%) 和有氧能力降低 (31%).
- 潜在的疾病与更高的复发率,肺部功能障碍和较差的运动能力有关.
结论:
- 儿童肺栓塞 (PE) 可以导致持续的功能缺陷,尽管大多数异常是暂时的.
- 潜在的条件显著影响PE复发和功能恢复.
- 在PE后的运动不耐受性往往是由于脱水,这强调了身体活动的重要性.
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