怀孕期间乙型肝炎病毒复制和围产期结果之间的关联:一项回顾性队列研究
Pingying Jiang1, Yongzhu Huang2, Kaiyi Mao1
1Department of Gastroenterology, Fujian Medical University Union Hospital, Fuzhou, China.
Annals of medicine
|December 22, 2023
概括
妊娠期间乙型肝炎病毒 (HBV) 复制增加了母亲剖腹产和婴儿新生儿黄的风险. 这项研究澄清了HBV复制对妊娠结果的影响.
科学领域:
- 产科和妇科 产科和妇科
- 肝病学 肝病学是一种肝病学.
- 围产儿医学 围产儿医学
背景情况:
- 妊娠期间乙型肝炎病毒 (HBV) 复制对母亲和婴儿结局的影响需要进一步调查.
- 了解这些关联对于管理HBV感染妇女的怀孕至关重要.
研究的目的:
- 调查HBV复制与孕妇的不良孕妇和婴儿结局之间的联系.
- 为了确定活跃的HBV复制是否存在超出标准妊娠并发症的风险.
主要方法:
- 从836名B型肝炎表面抗原阳性孕妇住院患者的临床数据的回顾性分析.
- 怀孕妇女与没有HBV复制之间的不良结果的比较,使用倾向性评分分析进行调整.
主要成果:
- 怀孕,高血压综合征,妊娠糖尿病,早产,巨,生长限制或阴道感染的肝脏内胆固醇症的发生率没有显著差异.
- 与非复制组相比,HBV复制组的剖腹产和新生儿黄率显著更高,即使经过调整.
结论:
- 母亲HBV复制与剖腹产风险增加有关.
- 出生于活跃HBV复制的母亲的婴儿患新生儿黄的风险更高.
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