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Updated: Jul 7, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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基因素脱乙酶网络调节HIV感染细胞中的表观遗传重编程和病毒沉默

Jackson J Peterson1, Catherine A Lewis1, Samuel D Burgos1

  • 1Department of Microbiology and Immunology, University of North Carolina (UNC) School of Medicine, Chapel Hill, NC 27514, USA; University of North Carolina HIV Cure Center, Institute of Global Health and Infectious Diseases, Chapel Hill, NC 27514, USA.

Cell chemical biology
|December 22, 2023
PubMed
概括

基斯脱乙酶 (HDAC) 酶对于维持潜伏的HIV储存器至关重要. 向HDAC1/2或HDAC3可以防止HIV潜伏期,而抑制所有三种可能会逆转它.

关键词:
克里斯普尔-Cas9是什么意思切割和运行 切割和运行在HDAC的基础上,HDAC是艾滋病毒治愈 治愈艾滋病毒艾滋病毒潜伏时间HIV潜伏时间艾滋病病毒-1 艾滋病病毒-1一个T细胞细胞.基因素乙化 基因素乙化 基因素乙化基因组脱乙酶 (Histone deacetylases) 是一种

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