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Updated: Jul 7, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

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针对IRE1的基于结构的药物设计:用于治疗癌症的基方法

Alireza Poustforoosh1, Sanaz Faramarz2, Mohammad Hadi Nematollahi2,3

  • 1Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Drug research
|December 22, 2023
PubMed
概括

新设计的针对因诺醇需要酶1 (IRE1) 的化合物显示出对癌症治疗的前途. 化合物17通过形成共价键,有效地抑制IRE1,这表明了新的治疗策略.

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