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Updated: Jul 7, 2025

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
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感官神经元促进肺部的免疫平衡

Masato Tamari1, Kate L Del Bel2, Aaron M Ver Heul3

  • 1Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mark Lebwohl Center for Neuroinflammation and Sensation, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pediatrics, Jikei University School of Medicine, Minato-ku, Tokyo 1058471, Japan; Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Setagaya-ku, Tokyo 1578535, Japan.

Cell
|December 22, 2023
PubMed
概括

亚努斯酶1 (JAK1) 在不同的组织中具有不同的作用. 在感觉神经元中,JAK1通过调节Calcb/CGRPβ来抑制呼吸道炎症,为精确医学提供了新的途径.

关键词:
一个 AAV美国CGRP其他:美国有关神经过敏性肺炎无形性疾病神经蛋白质感官神经元迷走神经

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