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胺质子转移权重的MRI用于脏瘤:与扩散权重成像的比较

Yun Xu¹, Qingxuan Wan¹, Xihui Ren¹

¹Department of Medical Imaging, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China; Institute of Medical Imaging Artificial Intelligence, Tongji University School of Medicine, Shanghai 200065, China.

Magnetic resonance imaging

|December 22, 2023

概括

胺质子转移加权 (APTw) MRI 在区分良性瘤和恶性瘤方面显示出前景. 这种技术可以作为癌诊断的有价值的成像生物标志物.

科学领域:

放射学和医学成像学医学成像学
在瘤学瘤学.
生物标志物发现发现

背景情况:

脏瘤是一个诊断挑战,需要准确区分良性和恶性类型.
多参数MRI,包括扩散权重成像 (DWI),用于脏瘤的特征.
需要新的MRI技术来提高诊断准确性和患者管理.

研究的目的:

评估胺质子转移加权 (APTw) 核磁共振成像在区分良性和恶性瘤中的有效性.
为了确定APTwMRI是否与扩散权重成像 (DWI) 结合时可以提高诊断性能.

主要方法:

术前多参数MRI,包括APTw MRI和DWI,在患有脏瘤的参与者身上进行.
对良性和恶性瘤计算了APTw值和明显扩散系数 (ADC) 值.
采用接收器操作特征 (ROC) 分析来评估APTw和ADC值的诊断性能.

主要成果:

与良性瘤相比,恶性脏瘤的平均APTw值显著高,ADC值较低.
对于APTw,ROC曲线下的面积 (AUC) 为0.78,ADC为0.70,组合为0.79.
APTw MRI证明了作为脏瘤分类的成像生物标志物的潜力.

结论:

APTw MRI显示了作为一种非侵入性成像生物标志物的潜力,用于区分良性和恶性瘤.
APTw MRI可能会为传统的MRI技术 (如DWI) 增加诊断价值,用于脏瘤评估.

关键词:

氨基酸质子转移加权 (APTw)扩散权重成像 (DWI) 是指扩散权重成像.磁共振成像 (MRI) 是一种磁共振成像.脏瘤是什么? 脏瘤是什么?

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Magnetic Resonance Imaging

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