在脊髓融合中脱矿化骨基和纤维
Joshua L Wang1, Ryan G Eaton2, Markus E Harrigan2
1Department of Neurological Surgery, The Ohio State University College of Medicine, Columbus, OH, USA Joshua.Wang@osumc.edu.
International journal of spine surgery
|December 22, 2023
概括
脱矿化骨基质 (DBM) 在脊柱融合手术中为自移植提供了一个可行的替代方案. 本综述详细介绍了DBM的产生及其成功骨形成的支持证据.
科学领域:
- 整形外科手术 整形外科手术
- 生物材料科学 生物材料科学
- 脊髓融合是指脊髓的融合.
背景情况:
- 关节骨折依赖于骨质诱导,骨质传导和骨质生成来进行骨融合.
- 自体移植是生物材料的传统来源,但往往不足.
- 现代脊椎手术使用骨移植替代品,如去矿物化骨基质 (DBM).
研究的目的:
- 为了回顾DBM的历史和生产.
- 介绍DBM应用的技术细节.
- 评估支持脊柱融合中DBM的证据.
主要方法:
- 关于骨移植历史的文献综述.
- 描述DBM的生产过程.
- 对脊柱融合的DBM进行临床研究的分析.
主要成果:
- DBM提供了骨质诱导和骨质导电性质.
- 证据支持DBM在促进脊柱融合方面的有效性.
- 在某些脊椎手术中,DBM可以扩展或取代自移植.
结论:
- 在脊柱融合中,DBM是自移植的有价值替代品.
- 了解DBM的生产和应用是至关重要的.
- 进一步的研究可能会在复杂的脊柱重建中完善DBM的使用.
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