乳清蛋白复合物与低强度运动相结合对老年 COPD 稳定阶段住院患者的作用
Min Zong1, Honghua Shen2, Lei Ren2
1Clinical nutrition center, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Asia Pacific journal of clinical nutrition
|December 22, 2023
概括
将乳清蛋白添加到肺康复 (PR) 中,改善了肌肉力量,减少了喘息和焦虑,并预防了老年COPD患者的体重减轻. 这种综合方法为COPD管理提供了显著的好处.
科学领域:
- 老年学是指老年学的学科.
- 肺部病理学 肺部病理学
- 营养科学 营养科学
背景情况:
- 肺部康复 (PR) 对慢性阻塞性肺部疾病 (COPD) 有效.
- 乳清蛋白作为口服营养补充剂 (ONS) 在PR期间的特定益处尚未得到充分证实.
- 之前的研究集中在全营养粉末上,在了解乳清蛋白的作用方面留下了一个空白.
研究的目的:
- 在老年COPD患者中,研究添加乳清蛋白复合物到PR的疗效.
- 为了比较单独的PR与与乳清蛋白的PR对运动能力,心理健康,肺功能和身体组成的影响.
- 为了确定乳清蛋白补充剂是否会提高超出标准PR的结果.
主要方法:
- 一项为期12周的随机试验,涉及90名老年COPD患者.
- 形成了三组:PR组,PR组加乳清蛋白复合体 (PRWP) 组,以及对照组.
- 评估的关键结果包括手握力 (HGS),6分钟步行距离 (6MWD),医学研究委员会呼吸障碍量表 (MRC),焦虑,肺功能和身体组成.
主要成果:
- 与对照组相比,PR和PRWP组的手握力都有所改善.
- 与对照组相比,PRWP组在6分钟步行距离 (6MWD) 中显著改善.
- 与PR组相比,PRWP组表现出更大的呼吸障碍 (MRC得分) 和焦虑的减少,以及体重增加.
结论:
- 肺部康复和乳清蛋白补充剂都能提高老年COPD患者的肌肉力量.
- 将乳清蛋白复合物添加到PR提供了额外的好处,包括改善呼吸障碍,减少焦虑和预防减肥.
- 这种综合康复策略可能是COPD老年患者的有价值的治疗选择.
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