使用尺度参数和最合适的对数增长曲线来描述头骨生长模式
Sungmi Jeon1, Jee Hyeok Chung2, Seung-Hak Baek3
1Department of Plastic and Reconstructive Surgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea; Division of Pediatric Plastic Surgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
概括
这项研究使用3DCT扫描对1000多名韩国儿童和青少年建立了特定于性别和年龄的头骨生长规范. 研究结果为诊断和治疗儿科关突症提供了必要的参考资料.
科学领域:
- 医疗成像医学成像
- 人类测量学 人类测量学.
- 儿科放射学 儿科放射学
背景情况:
- 从婴儿期到成年期的大脑生长的定量数据有限.
- 建立特定于性别和年龄的规范对于儿科头骨评估至关重要.
研究的目的:
- 在韩国人口 (0-18岁) 中描述头骨生长模式.
- 建立关键的头骨测量参数的性别和年龄特定的规范数据.
- 提供用于诊断和治疗儿科头骨异常的参考数据库.
主要方法:
- 利用1009名韩国患者的薄切片计算机断层扫描 (CT) 扫描.
- 已建立的参考平面 (法兰克福水平,中腰,冠状) 用于测量.
- 使用Mimics软件测量了内体积 (ICV),前后直径 (APD),双直径 (BPD) 和高度 (CHs).
- 使用线性回归推导出最合适的对数曲线.
主要成果:
- 在年龄调整后,男性的ICV,APD,BPD和CHs比女性高 (p < 0.0001).
- 在生命早期,ICV,APD,BPD和CHs迅速增加,在5-6岁时达到成年人体积的90-95%.
- 头脑指数 (CI) 和身高指数 (HI) 显示,随着年龄的增长,无论性别如何,都会持续下降4%.
结论:
- 这项研究为韩国人高达18岁的人提供了全面的头骨生长参考.
- 已建立的规范可以帮助诊断和治疗计划的儿科关突症.
- 提供了宝贵的定量数据,用于儿童的头骨重建指导.
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