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在炎症期间,TRIM25决定了选择性miRNA在细胞外囊泡中加载

Kayla E King1,2, Priyanka Ghosh1,2, Ann L Wozniak3,4

  • 1Department of Internal Medicine, University of Kansas Medical Center, Mailstop 1018, Kansas City, KS, 66160, USA.

Scientific reports
|December 22, 2023
PubMed
概括

炎症促使RNA结合蛋白FMR1和microRNAmiR-155进入细胞外囊泡 (EVs). 这个过程是由E3结合酶TRIM25控制的,它在FMR1中无处不在,影响EV生物发生.

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