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NUAK1协调mTORC2和Akt信号的增长因子依赖激活

Mario Palma1, Elizabeth Riffo2, Alejandro Farias2

  • 1Laboratorio de Transducción de Señales y Cáncer, Departamento de Bioquímica y Biología Molecular, Facultad Cs. Biológicas, Universidad de Concepción, Concepción, Chile. mpalma@hsph.harvard.edu.

Cell & bioscience
|December 22, 2023
PubMed
概括

酶调节生长因子激活的Akt信号,通过控制mTORC2的局部化和直接酸化Akt. 向NUAK1可以通过过度激活的Akt信号来治疗癌症.

关键词:
标签: 活动 活动 活动癌症信号传递 癌症信号传递协同准是一种共同准.在 NUAK1 中,NUAAK1在 mTORC2 中,mTORC2 是

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