相关实验视频
Updated: Jun 15, 2026
10:02
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
24.3K
过早出生的年轻女性的手握力比她们的满期出生的同龄人弱
Ella Bruun1,2,3, Pauli Pätsi1,2,3, Markku Leskinen1,2,3
1Department of Pediatrics, Oulu University Hospital, University of Oulu, Wellbeing Services County of North Ostrobothnia, 90220 Oulu, Finland.
Children (Basel, Switzerland)
|December 23, 2023
概括
过早出生的年轻人,尤其是女性,表现出下手握力. 在这个群体中,维生素D补充剂没有改善肌肉力量,这表明肌肉健康状况下降的持续风险.
科学领域:
- 生理学 生理学 生理学
- 新生儿科学 新生儿科学
- 内分泌学 在内分泌学.
背景情况:
- 过早生育与肌肉健康的长期缺陷和增加的发病率有关.
- 手握强度是肌肉强度的关键指标,但其与早产和维生素D的关系尚未完全理解.
- 之前关于维生素D在肌肉力量中的作用的研究已经产生了不一致的结果.
研究的目的:
- 为了研究年轻成年人早产的手握强度,与全产期对照进行比较.
- 评估一年的维生素D补充剂对该队列手握强度的影响.
- 探索维生素D状态,人体测量和肌肉力量之间的潜在关联.
主要方法:
- 招募了38名早产的年轻成年人 (孕期≤32或<34周,<1500克) 和39名匹配的对照.
- 在基线和1年维生素D补充剂后,测量了人类学,手握强度和维生素D度.
- 使用统计分析,包括t测试和线性回归来比较组和识别关联.
主要成果:
- 与对照组 (30.7%,p=0.009) 相比,早产的年轻人表现出明显较低的年龄和性别特定的手握强度排名 (57.9%低于平均水平).
- 过早出生的女性的手握强度明显低于她们的满期同龄人 (平均差异为-3.46公斤,p=0.035).
- 在早产女性中,成年人身高与手握力有负相关性 (R2=0.24,p<0.001);维生素D补充剂增加了维生素D水平,但没有手握力.
结论:
- 早产的年轻女性有较高的肌肉力量降低的风险,无论他们目前的维生素D状况如何.
- 一年多的维生素D补充剂并没有提高健康早产的年轻成年人的手握力.
- 这些发现强调了早产对肌肉健康的潜在长期后果,特别是在女性身上.
相关概念视频
01:09Changes in the Appendicular Skeleton with Age
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
01:16Muscles of the Forearm that Move the Hand and Fingers
The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi radialis,...
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi radialis,...