叶低成形是否会影响白化患者的化?
Line Kessel1,2, Christine Dahlgren Bohnsack Kjølholm1, Joaquim Torner Jordana1
1Department of Ophthalmology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.
Children (Basel, Switzerland)
|December 23, 2023
概括
像高视度和纹等折射错误在白化患者中很常见. 凝膜化很少发生,形发育不会影响折射结果,支持早期纠正.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
背景情况:
- 白化症是一组遗传性疾病,其特点是缺乏色素.
- 目和眼皮白化现象与显著的视力障碍.
- 白白症的折射发育没有得到充分的证据.
研究的目的:
- 描述丹麦白化患者从童年到成年期的折射发育情况.
- 评估发育对折射结果的影响.
- 为了告知临床管理的折射误差在白化.
主要方法:
- 招募了白化症患者进行折射评估和表型化.
- 使用光学连贯断层扫描 (OCT) 来分级叶低成形 (0-4).
- 检查医疗记录以查看历史的折射数据.
主要成果:
- 超视 (≥+1D) 的流行率为:儿童为81.3%,成人为67.1%.
- 随着年龄的增长,阿斯蒂格马蒂斯症的增加解释了成年人中视障的减少.
- 凝血化 (>2D变化) 仅发生在22.2%的患者中.
- 叶低成形等级没有影响折射误差的严重程度.
结论:
- 在白白症患者中,化不常见.
- 状发育阶段不会影响折射误差分布.
- 高度超视和形是常见的;建议早期进行折射校正.
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