恶性肺半径瘤的当前治疗格局和未来的方向
Beatriz Bertin1, Miguel Zugman2, Gustavo Schvartsman2
1Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo 05651-901, Brazil.
Cancers
|December 23, 2023
概括
恶性多叶层层层瘤的新疗法正在出现,包括疫苗,工程T细胞和化疗免疫疗法,以对抗这种具有挑战性的癌症并改善患者的生存率.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 癌症生物学 癌症生物学
背景情况:
- 全球恶性多叶层层层瘤的发病率正在上升.
- 目前的治疗选择有限,需要新的方法.
- 瘤异质性和低突变负担带来了治疗挑战.
研究的目的:
- 审查最近恶性多叶膜间皮瘤治疗的进展.
- 分析相关临床试验数据.
- 突出未来有希望的治疗策略.
主要方法:
- 审查最近的临床试验和研究数据.
- 对治疗疗效和挑战的分析.
- 识别新兴的治疗方式.
主要成果:
- 针对性治疗没有建立单一的生物标志物.
- 结合策略通常是改善结果的必要条件.
- 有希望的选择包括本地应用的疫苗,工程T细胞和免疫检查点封锁.
结论:
- 免疫疗法和化疗免疫疗法的进步对间皮瘤有希望.
- 结合策略对于克服治疗耐药性至关重要.
- 预计这些新的方法将大大改变中瘤治疗的前景.
相关概念视频
Pleural Disorders: Types and Brief Description
209
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
209
Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
Pleural Effusion II: Symptoms and Management
181
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
181
Pleura of the Lungs
1.9K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
1.9K


