应急部门的抗生素准则遵守:来自具有限制性抗生素政策的国家的描述性研究
Mariana B Cartuliares1,2, Sara N Søgaard1,2, Flemming S Rosenvinge3,4
1Department of Emergency Medicine, University Hospital of Southern Denmark, 6200 Aabenraa, Denmark.
Antibiotics (Basel, Switzerland)
|December 23, 2023
概括
医生经常使用广谱抗生素治疗社区获得性肺炎 (CAP),尽管丹麦.
科学领域:
- 传染性疾病 传染性疾病
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 丹麦的抗菌素耐药性 (AMR) 很低.
- 疑似感染的非特异性症状会导致诊断不确定性.
- 医生们面临着在遵循指导方针的窄谱抗生素和宽谱抗生素之间的困境.
研究的目的:
- 评估对社区获得性肺炎 (CAP) 的限制性抗生素指南的遵守情况.
- 评估丹麦紧急服务部门 (ED) 的抗生素处方做法.
主要方法:
- 多中心描述性横截面研究.
- 从丹麦ED的成年患者的医疗记录收集前性数据.
- 对954名怀疑感染的患者的分析.
主要成果:
- 遵守CAP实证抗生素治疗指南的比例很低 (31.3%).
- 带有β-乳糖酶抑制剂的青素是最常被处方的抗生素.
- 静脉注射抗生素最初很常见 (4小时60.7%),到第5天 (54.4%) 转向口服.
结论:
- 对农业政策指导方针的遵守情况不佳.
- 广泛的抗生素经常被使用,这与限制性抗生素政策设置中的建议相反.
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