来自处理设施的耐金属微生物的抗生素耐药性
Leonid Perelomov1, Olga Sizova2, Maria Gertsen1
1Laboratory of Biogeochemistry, Tula State Lev Tolstoy Pedagogical University (Tolstoy University), Lenin Avenue, 125, Tula 300026, Russia.
Antibiotics (Basel, Switzerland)
|December 23, 2023
概括
废水中的耐金属细菌表现出抗生素耐药性,这表明重金属可能驱动这种现象. 这项研究强调了重金属污染与城市环境中抗生素耐药性的传播之间的联系.
科学领域:
- 环境微生物学 环境微生物学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 污水处理厂 (WWTP) 是耐金属细菌的储存库.
- 重金属污染是一个日益严重的环境问题.
研究的目的:
- 调查来自一个大城市的WWTP的耐金属细菌的抗生素耐药性模式.
- 探索重金属对抗生素耐药性的潜在共同选择.
主要方法:
- 从污水污泥中分离和识别耐金属细菌.
- 测试细菌对多种重金属 (Cu,Pb,Zn) 的耐药性.
- 评估细菌对各种类型抗生素 (β-乳糖类,氨基糖类,安非尼醇,四环素等) 的敏感性. ) 的情况.
主要成果:
- 大多数耐金属分离体对多种抗生素表现出耐药性.
- 克莱布西拉肺炎菌株是一个例外,没有显示抗生素耐药性.
- 塞拉蒂亚fonticola和Stenotrophomonas maltophilia菌株表现出高水平的抗生素耐药性.
结论:
- 细菌对抗生素的耐药性可能会通过WWTP中的重金属污染共同选择.
- 重金属可能在发展和维持抗生素耐药性的过程中发挥作用.
- 研究结果表明,重金属和抗生素耐药性机制之间存在复杂的相互作用.
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