初级保健 抗生素处方和与感染相关的住院治疗
Stein Gerrit Paul Menting1, Enya Redican1, Jamie Murphy1
1School of Psychology, Ulster University, Coleraine BT52 1SA, UK.
Antibiotics (Basel, Switzerland)
|December 23, 2023
概括
在初级保健中不适当的抗生素处方有助于抗菌素耐药性,并增加感染住院治疗. 适当的处方可能会减少住院,但过度使用会增加风险,突出需要更好的管理和诊断.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗菌素耐药性 (AMR) 是全球主要的健康威胁,主要是由不适当的抗生素处方驱动的.
- 初级保健机构占抗生素处方的大部分,这使得它们成为了解AMR的关键焦点.
- 初级保健抗生素使用与感染相关住院等长期健康结果之间的联系需要进一步调查.
研究的目的:
- 审查关于初级保健抗生素处方和随后感染相关住院治疗之间的关联的科学文献.
- 了解初级保健抗生素干预对患者健康结果的影响.
- 确定影响初级保健中抗生素处方决策的因素.
主要方法:
- 进行了对研究的叙述性审查.
- 用Web of Science数据库进行文献搜索.
- 检索了252项可能相关的研究,并将23项纳入最终审查,按患者年龄和感染类型分层.
主要成果:
- 一些研究表明,在初级保健中适当的抗生素处方可以减少住院治疗.
- 相反,过度的抗生素处方与抗菌素耐药性增加和感染相关住院住院的风险增加有关.
- 一个子集的研究发现,初级保健抗生素处方和随后的住院治疗之间没有显著的关联.
结论:
- 初级保健抗生素处方和感染相关住院治疗之间的关系是复杂的,受到多种因素的影响.
- 在初级保健中需要以患者为中心的抗生素管理计划.
- 建议在初级保健机构增加快速诊断测试的使用,以优化抗生素处方.
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