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Updated: Jul 7, 2025

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气体6轴信号诱导SRF/MRTF-A通过MICAL2进行基因转录

Mark R Lundquist1, Samie R Jaffrey1

  • 1Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA.

Genes
|December 23, 2023
PubMed
概括

增长停止特异性蛋白6 (GAS6) 和它的受体Axl激活血清反应因子 (SRF) /肌肉相关的转录因子-A (MRTF-A) 转录. 在Gas6/Axl通路中,MICAL2作为一种新型的效应剂,促进基因转录和细胞入侵.

关键词:
在 Axl Axl 轴上气体6 是一个气体.这就是MICAL2的意义.在MRTF-A中,血清反应因子是血清反应因子.

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