甲基糖结晶对W/O/W乳液稳定性,控制释放性和体外消化能力的影响
Chaoying Qiu1, Yingwei Liu2, Canfeng Chen1
1JNU-UPM International Joint Laboratory on Plant Oil Processing and Safety, Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
Foods (Basel, Switzerland)
|December 23, 2023
概括
滴糖醇 (DAG) 晶体在水中油中水乳液中形成坚固的外,增强物理稳定性,改善生物活性封装和输送. 这些DAG稳定乳液可以更好地控制释放特征和体外消化.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学是一种材料科学.
- 制药科学 制药科学
背景情况:
- 水中的油中的水 (W/O/W) 乳液是多功能输送系统.
- 提高生物活性化合物在乳液中的物理稳定性和受控释放仍然是一个挑战.
- 甲基甘油 (DAG) 具有创造稳定的界面结构的潜力.
研究的目的:
- 制造和优化W/O/W乳液,其中包含高化糖醇 (DAG) 晶体.
- 评估DAG晶体对乳液物理稳定性,封装效率和体外释放的影响.
- 评估DAG稳定乳液对水和油溶性生物活性物的体外消化和生物可访问性的影响.
主要方法:
- 制造具有不同DAG度的W/O/W乳液.
- 优化乳液成分的物理稳定性.
- 对透压和加热的稳定性进行评估.
- 对表甲基酸盐 (EGCG) 和黄素的封装效率的测量.
- 盐和生物活性物质的体外释放研究.
- 在体外消化试验测试以确定生物可访问性.
主要成果:
- 表面结晶的DAG外显著增强了对透压力和热量的乳液稳定性.
- 在W1/O接口和内相凝中的DAG晶体减少了滴滴大小和减缓了盐分释放.
- 含有DAG和凝的乳液显示,对EGCG等生物活性物质的封装效率和储存稳定性有所改善.
- 在DAG稳定双乳液中,消化速度降低,但EGCG和黄素的生物可访问性增加.
结论:
- 具有凝内相的DAG稳定双乳液提供了强大的界面晶体外.
- 这些系统提供了增强的物理稳定性和封装生物活性物质的控制释放.
- DAG稳定乳液有望用于应用,作为营养药和药品的先进控制输送系统.
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