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在 Preserflo MicroShunt 影响微血管流密度在光学一致性断层扫描血管图

Jens Julian Storp¹, Hannah Schatten^1,2, Friederike Elisabeth Vietmeier¹

¹Department of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.

|December 23, 2023

概括

在青光眼患者中,Preserflo MicroShunt有效降低眼内压力 (IOP). 然而,它引起了周周状视网膜流动密度的显著下降,特别是在晚期玻璃眼中.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
微血管成像技术微血管成像技术

背景情况:

玻璃眼瘤手术可以影响眼睛的微血管结构.
在降低眼内压力 (IOP) 程序后,了解视网膜流密度 (FD) 的变化至关重要.

研究的目的:

在Preserflo MicroShunt植入后,使用光连贯断层扫描血管造影 (OCTA) 评估视网膜流密度 (FD) 的变化.
评估在不同视网膜结合体的内缩减和FD变化之间的相关性.

主要方法:

对34只接受Preserflo MicroShunt植入的眼睛进行前性研究.
在表面 (SCP),深层 (DCP) 和辐射周状 (RPC) 层面进行OCTA成像.
从基线到术后六个月的FD和IOP的评估.

主要成果:

普雷斯弗洛MicroShunt显著降低了内血压 (中位数:8mmHg;p <0.01).
没有观察到SCP和DCP流密度的显著变化.
发生了RPC流密度的显著下降 (42.31到39.59;p < 0.01),最明显的是晚期玻璃眼.

结论:

普雷斯弗洛MicroShunt有效降低内压,但影响周周毛囊微血管.
晚期玻璃眼病患者表现出更大的周围毛囊流密度减少,这表明自身调节受损.
黄斑微血管似乎更适应手术后的IOP变化.

关键词:

IOPOP IOPOP IOPOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP IOP 照亮了他们的灯光.这就是MIGS.设备设备设备设备玻璃眼 glaucoma 玻璃眼玻璃眼玻璃眼玻璃眼眼内压力眼内压力严重程度的严重程度.手术手术手术手术手术手术手术船舶密度是指船舶的密度.

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Blood Flow

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.