整体关节置换感染:对文献的系统审查
Renato Zunarelli1, Michele Fiore1, Gianluca Lonardo1
1Orthopedic and Traumatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Journal of clinical medicine
|December 23, 2023
概括
完全关节置换 (TAR) 后的周围假肢关节感染 (PJI) 是一种严重的并发症. 这次审查发现PJI的平均发病率为3.8%,大多数病例是晚发性感染,需要复杂的管理.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 周围假肢关节感染 (PJI) 是完全关节置换 (TAR) 后的一个重大并发症.
- PJI的管理可能需要修复关节整形,脚合或截肢.
- 了解TAR PJI的流行病学和治疗对于患者的治疗结果至关重要.
研究的目的:
- 系统地审查和总结有关TAR PJI管理的当前证据.
- 提供TAR PJI的全面概述,重点关注流行病学方面.
- 确定有关TAR PJI治疗和结果的文献上的空白.
主要方法:
- 对三个数据库 (PubMed,Scopus,Web of Science) 的系统审查和交叉引用.
- 包括71项报告TAR PJI病例的研究.
- 对298个已检索的PJI病例进行分析.
主要成果:
- 治疗后PJI的平均发病率为3.8% (范围为0.2-26.1%).
- 17.8%的PJI是急性,而52.3%是晚发性.
- 两个阶段的外科手术方法是最常见的治疗方法 (35.9%),尽管方案异质.
结论:
- 脚PJI虽然发病率很低,但是TAR的毁灭性并发症.
- 有一个显著的缺乏关于TAR感染的强大的文献.
- 需要使用标准化数据进行多中心研究,以提高对脚PJI的理解和治疗.
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