药理治疗策略与老年患者心房的认知功能之间的关系
Markus Goetze1, Tim Knauf2, Henning Ebelt2
1Department for Geriatrics, St. Elisabeth Hospital, Bahnhofstrasse 19, 99976 Lengenfeld unterm Stein, Germany.
Journal of clinical medicine
|December 23, 2023
概括
大多数患有心房动 (AF) 的老年患者接受速率控制疗法. 口服抗凝药改善了迷你精神状态 (MMS) 评分,而抗血小板药物与AF患者的MMS恶化有关.
科学领域:
- 老年病的医生 老年病的医生
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 心房动 (AF) 是一种普遍的心律失常.
- 老年患者代表着受AF影响的显著人群.
研究的目的:
- 调查AF老年患者的治疗策略 (节律与速率控制).
- 在这个人口群体中探索AF治疗和迷你精神状态 (MMS) 之间的关联.
主要方法:
- 前性,观察性,单心研究.
- 收集关于慢性药物,人口统计,心电图和MMS的数据.
- 分析了715名有AF史的老年患者.
主要成果:
- 94%的AF患者接受了速率控制治疗;6%接受了节律控制.
- 速率和节律控制组之间的MMS没有显著差异.
- 口服抗凝剂 (OAC) 与改善的MMS相关;抗血小板药物与减少的MMS相关.
结论:
- 节拍控制是老年AF患者的主要策略.
- 在老年AF患者中,OAC与更好的认知功能 (MMS) 有关.
- 抗血小板治疗可能会对这一群体的MMS产生负面影响.
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