11/19-B1从基维果中分离出来,作为一种潜在的益生菌和副益生菌
Ken Ishioka1, Nozomu Miyazaki1, Kyoko Nishiyama1
1Department of Microbiology, School of Medicine, Fukushima Medical University, Fukushima 960-1295, Japan.
Microorganisms
|December 23, 2023
概括
乳球菌乳酸菌11/19-B1,一种来自果的益生菌,显示出食品工业的潜力. 它表现出有益的特性,如抗微生物活性和在模拟的肠道条件下生存,这表明它可以作为益生菌或类益生菌使用.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 免疫学 免疫学 免疫学
背景情况:
- 益生菌是提供健康益处的活微生物.
- 从果中分离出来的乳球菌11/19-B1已经显示出免疫调节作用.
- 之前的研究表明,它有潜力降低LDL,改善亚托邦性皮炎.
研究的目的:
- 评估乳球菌乳酸菌的益生菌和副益生菌潜力 11/19-B1.1.
- 评估其食品应用的安全性和功能特性.
主要方法:
- 抗菌素敏感性测试. 抗菌素敏感性测试.
- 生物原氨酸生产分析.
- 病毒性基因查.病毒性基因查.
- 抗菌活性测定. 抗菌活性测定.
- 对胃酸和胆汁酸的耐受性测试.
- 肠道细胞粘附试验 (Caco-2细胞).
主要成果:
- 11/19-B1菌株对大多数测试的抗微生物药物表现出敏感性,除了素和菌素.
- 没有检测到有害的生物氨基胺生产.
- 存在抗微生物活性,但对Caco-2细胞的附着性不存在.
- 这种菌株在0.3%的胆盐中存活下来,而不是1%的胆盐.
- 在与脱脂牛奶模拟的胃肠条件下,在4小时后观察到67%的生存率.
结论:
- 乳球菌11/19-B1表现出适合益生菌或偏益生菌使用的特征.
- 它的安全性和功能性质要求对食品工业应用进行进一步的研究.
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