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威利斯圆圈配置和血栓定位对缺血性中风患者结果的影响:系统性审查
Audrius Širvinskas1,2, Givi Lengvenis1,2, Giedrius Ledas1
1Medical Faculty, Vilnius University, M. K. Čiurlionio g. 21, LT-03101 Vilnius, Lithuania.
Medicina (Kaunas, Lithuania)
|December 23, 2023
概括
威利斯的圆圈是威利斯的圆圈.
科学领域:
- 神经学 神经学
- 血管神经学 血管神经学
- 神经科学是一个神经科学.
背景情况:
- 威利斯圆的完整性对于中风的结果至关重要,特别是在内动脉封闭的情况下.
- 威利斯圆的变化可能会影响附带循环和缺血性中风患者的预后.
- 了解这些解剖学因素是治疗中风患者的关键.
研究的目的:
- 审查现有的关于威利斯圆配置对缺血性中风结果影响的文献.
- 分析血栓位置和威利斯圆变异对患者预后的影响.
- 综合当前关于抵押流和中风严重性的证据.
主要方法:
- 在PubMed,Cochrane和EMBASE数据库中进行系统的文献搜索,截至2023年3月.
- 遵守PRISMA指南的研究选择和数据提取.
- 使用MINORS标准进行包含研究的质量评估.
主要成果:
- 包括11项研究 (n=4643),突出了威利斯圆完整性在中风结果中的作用,特别是T型闭塞.
- 威利斯圆的配置在M1阻塞中不那么重要,但在远端内动脉阻塞中至关重要.
- 一个完整的逆侧A1段和前沟通动脉对于远端内动脉阻塞的良好结果至关重要.
结论:
- 维护威利斯圆的完整性显著影响附带流并改善缺血性中风患者的结果.
- 受中风影响的大脑区域的范围与临床结果相关;单一区域的参与与更好的预后有关.
- 威利斯圆的解剖学变化是中风严重程度和恢复潜力的重要决定因素.
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