无形皮肤炎和感染的风险在末期脏病的感染风险
Rushan I Momin1, Stephanie L Baer1,2, Jennifer L Waller1
1Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Medicina (Kaunas, Lithuania)
|December 23, 2023
概括
亚托皮性皮肤炎 (AD) 增加了末期病 (ESRD) 患者的感染风险. 在ESRD患者中,阿尔茨海默病与较高的蜂炎和疹发病率有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
背景情况:
- 亚托匹性皮肤炎 (AD) 或湿疹是一种慢性炎症性皮肤疾病,影响数百万人.
- 阿尔茨海默病涉及皮肤屏障受损,增加对感染的易感性.
- 末期病 (ESRD) 患者因透析和免疫功能障碍而面临感染风险.
研究的目的:
- 调查亚托皮性皮肤炎 (AD) 是否是末期病 (ESRD) 患者特定感染的危险因素.
主要方法:
- 从2004年至2019年开始透析的成年ESRD患者的回顾性队列分析.
- 使用美国脏数据系统 (USRDS) 来提取数据.
- 检查了AD诊断和结果之间的关联,包括细菌病,败血症,细胞炎,疹和结膜炎.
主要成果:
- 在1526,266名ESRD患者中,0.2%患有AD.
- 阿尔茨海默病与细胞炎 (aRR=1.39) 和疹 (aRR=1.67) 的风险增加有关.
- 在阿尔茨海默病和细菌病,败血症或结膜炎之间没有发现显著的关联.
结论:
- 皮炎 (AD) 与某些感染的风险增加有关,特别是细胞炎和疹,在末期脏疾病 (ESRD) 患者中.
- 这些发现强调了将AD视为ESRD人群中特定感染的风险因素的重要性.
- 进一步的研究可能是合理的,以探索这种关联背后的机制.
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