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扩散权重MRI在直肠癌中的多用途使用

Aneta Yacheva¹, Dragomir Dardanov², Dora Zlatareva¹

¹Department of Diagnostic Imaging, University Hospital Alexandrovska, Medical University of Sofia, 1431 Sofia, Bulgaria.

Medicina (Kaunas, Lithuania)

|December 23, 2023

概括

在直肠癌中,明显扩散系数 (ADC) 的测量低于健康组织,与瘤阶段和血管入侵相关. ADC可以预测治疗反应,有助于规划直肠癌疗法.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

结肠直肠癌是全球主要的瘤疾病之一.
局部晚期直肠瘤的标准治疗包括新辅助放射化疗和手术.
磁力共振成像 (MRI) 发现对于治疗计划至关重要.

研究的目的:

评估明显扩散系数 (ADC) 测量在直肠癌中的作用.
探索ADC在各种临床场景中的实用性.
在新辅助化疗或放射治疗后评估ADC变化.

主要方法:

在135名患者进行了直肠MRI (75名直肠腺癌患者,60名无病患者).
从感兴趣的区域获得了明显扩散系数 (ADC) 测量结果.
18名直肠癌患者接受了第二次MRI后neoadjuvant化疗放射治疗以进行ADC比较.

主要成果:

结直肠癌的ADC值明显低于对照组 (p < 0.001).
较低的ADC值与较高的T阶段 (p = 0.039) 和外壁血管侵入 (p = 0.01) 相相关.
治疗后ADC值显著增加 (p < 0.001),较低的初始ADC预示着更大的增加 (r = -0.6572,p = 0.004).

结论:

在评估直肠癌方面,ADC测量提供了补充作用.
ADC在预测化疗或放射治疗反应方面具有潜力.
ADC可以改善直肠癌治疗策略的规划.

关键词:

这是一个ADCADC ADC.这就是为什么MRI是MRI.化学疗法或放射治疗这是直肠癌.

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