生物活性乳制品发酵制品和化合物:一起或单独使用
Barbara Wróblewska1, Aleksandra Kuliga1, Kinga Wnorowska1
1Institute of Animal Reproduction and Food Research, Polish Academy of Science, 10-748 Olsztyn, Poland.
将乳制品蛋白与EGCG和CGA等植物聚醇结合起来,可以降低牛奶的过敏性并增强健康益处. 这些新型结合物可以作为代谢前生物,促进肠道健康和减少炎症.
科学领域:
- 食品科学 食品科学 食品科学
- 营养生物化学 营养生物化学
- 计算生物学 计算生物学
背景情况:
- 发酵乳制品由于其生物活性和免疫活性降低,因此具有健康益处.
- 植物性多 (例如,黄,酸) 以其抗炎和减轻慢性疾病的特性而闻名.
- 将乳制品蛋白与多相结合正在探索,以增强生物活性并创造新的功能成分.
研究的目的:
- 研究特定的多 (EGCG,CGA) 与牛奶蛋白 (例如α-乳蛋白,β-乳球蛋白,素) 的结合.
- 评估这些蛋白质多联体在降低牛奶蛋白质过敏性方面的潜力.
- 探索这些结合物作为代谢前生物的作用及其对肠道微生物群的影响.
主要方法:
- 使用in silico对接模拟来建模蛋白质-多相互作用.
- 结合结构的分析和相互作用的预测后果.
- 评估潜在的益生菌效应和对细菌生长的影响 (致病性与有益).
主要成果:
- 乙甲基-3-酸 (EGCG) 和酸 (CGA) 具有与主要牛奶蛋白结合的倾向.
- 预计蛋白质多联体的形成会改变蛋白质结构,并可能降低过敏性.
- 结合物显示出作为代谢前生物的潜力,促进有益的肠道细菌并抑制致病性细菌.
结论:
- 乳制品蛋白质-多联体代表了开发具有增强健康益处的低过敏性乳制品的有希望的战略.
- 这些合物可以作为功能成分,调节肠道微生物群并产生抗炎作用.
- 在 silico 方法是预测新型食品衍生生物活性物质的结构和功能的有价值的工具.
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