益生菌在术后疼痛管理中的作用
Barbara Fyntanidou1, Aikaterini Amaniti2, Eleftheria Soulioti3
1Department of Emergency Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Journal of personalized medicine
|December 23, 2023
概括
手术后的疼痛受到手术后肠道微生物组变化的影响. 补充特定的益生菌菌株可能有助于通过独特的机制缓解这种疼痛.
科学领域:
- 胃肠病学 胃肠病学
- 疼痛管理 疼痛管理
- 微生物学 微生物学
背景情况:
- 术后疼痛是由于手术创伤和内脏感应器激活而产生的.
- 肠道微生物组在麻醉和手术过程中被显著改变.
- 肠道微生物组在疼痛感知中起着至关重要的作用.
研究的目的:
- 分析当前关于肠道微生物组与术后疼痛之间的关系的知识.
- 评估益生菌在治疗术后疼痛方面的潜力.
- 了解益生菌对缓解疼痛的菌株特异性影响.
主要方法:
- 关于肠道微生物组和疼痛的实验研究的综述.
- 对调查手术后益生菌干预的研究进行分析.
- 专注于不同益生菌菌株的作用机制.
主要成果:
- 麻醉和手术会破坏肠道微生物群.
- 益生菌补充剂在恢复肠道平衡方面表现有前途.
- 证据表明,在不同益生菌菌株中,疼痛缓解的机制各不相同.
结论:
- 通过益生菌恢复受损的肠道微生物组是术后疼痛管理的可行策略.
- 每种益生菌菌株对缓解疼痛有独特的作用.
- 对菌株特异性疗效的进一步研究是有必要的.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
88
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
88
Peptic Ulcer Disease V: Surgical Management and Nursing Care
308
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
308
Analgesia and Pain Management
628
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
628
Inflammatory Bowel Disease V: Surgical Management
148
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
148
Peptic Ulcer Disease IV: Management
95
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
95
Drugs for Treatment of Constipation-Predominant IBS
176
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
176


