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唾液细胞外囊泡:在人类疾病中的生物标志物和超越

Jialing Wu¹, Gege Liu¹, Rong Jia¹

¹State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China.

International journal of molecular sciences

|December 23, 2023

概括

唾液细胞外囊泡显示为诊断疾病的非侵入性生物标志物具有前途. 本综述强调了它们的诊断潜力和在口腔和非口腔条件下的各种功能.

科学领域:

生物化学生物化学
分子生物学分子生物学
生物医学诊断生物医学诊断

背景情况:

细胞外囊泡 (EVs) 是参与细胞间通信的生物活性分子.
电动体因其在各种病理生理过程中的作用以及作为潜在的诊断生物标志物而得到认可.
唾液是一种易于获得的含有EVs的生物流体,为分析提供了对其他体液的非侵入性替代品.

研究的目的:

审查唾液细胞外囊泡 (sEVs) 作为临床诊断生物标志物的新兴作用.
要总结目前对sEV生物发生,内容和功能的理解.
探索sEVs在诊断口腔和非口腔疾病中的潜在应用.

主要方法:

关于唾液细胞外囊泡的最近研究的文献综述.
对研究研究SEVs的诊断潜力的分析.
收集关于SEVs在健康和疾病中的功能作用的数据.

主要成果:

唾液中的细胞外囊泡越来越多地被研究它们的生物标志物潜力.
唾液为基于EV的诊断提供了一个方便而非侵入性的来源.
sEVs涉及到诊断之外的功能,包括静血和免疫防御.

结论:

唾液细胞外囊泡代表了对非侵入性诊断工具的有希望的前沿.
对sEV的进一步研究可以显著推进早期疾病检测和监测.
了解sEVs的多方面的作用可以导致新的治疗策略.

关键词:

生物标志物生物标志物细胞外囊泡中的细胞外囊泡.口腔疾病口腔疾病这是唾液,唾液.

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