相关实验视频
Updated: Jul 7, 2025

09:36
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
27.1K
儿童肥胖:洞察脏参与的方法
Nazareno Carullo1, Mariateresa Zicarelli1, Ashour Michael1
1Department of Health Sciences, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.
International journal of molecular sciences
|December 23, 2023
概括
儿童肥胖越来越多地影响脏健康,与糖尿病和高血压有关. 在肥胖儿童中早期发现损伤对于更好的结果至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
背景情况:
- 儿童肥胖和慢性病 (CKD) 在全球范围内正在上升.
- 肥胖与末期病 (ESRD) 的主要原因有关,包括糖尿病 (DM) 和高血压.
- 肥胖对儿童CKD的影响虽然比成年人研究得少,但显示出令人担忧的趋势.
研究的目的:
- 审查当前关于儿童肥胖对脏健康影响的数据.
- 探索肥胖儿童损害的流行病学,病原遗传学,临床和病理学方面.
- 为儿科医生和科医生提供最新发现和挑战的信息.
主要方法:
- 对流行病学,病原遗传学,临床和病理学研究的综合文献综述.
- 分析肥胖,代谢综合征,胰岛素抵抗和病之间的关联.
- 探索阿迪波金和脂肪组织-脏轴的作用.
主要成果:
- 肥胖会通过代谢综合征和胰岛素抵抗导致脏损伤.
- 脂肪组织衍生的阿迪波金可以诱导纤维化.
- 肥胖会对脏移植结果产生负面影响.
- 早期脏干扰通常无症状,并未被标准标志物检测到.
结论:
- 在肥胖儿童中早期发现损伤至关重要.
- 新型生物标志物和蛋白质组学等技术对于早期诊断至关重要.
- 对遗传因素,并发症和生物标志物的进一步研究可以改善预后并指导新的治疗策略.
相关概念视频
External Anatomy of the Kidney
1.1K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.1K
Obesity
507
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
507
Overview of Protein Metabolism
1.2K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
1.2K
Internal Anatomy of the Kidney
1.8K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
1.8K
Nephrons
2.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications
553
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
553

