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Updated: Jul 7, 2025

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异常的胆固醇代谢和溶酶体功能障碍通过抑制mTORC1-TFEB-依赖自会诱导与年龄相关的听力损失

Yun Yeong Lee1, Jungho Ha1,2, Young Sun Kim1

  • 1Department of Otolaryngology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.

International journal of molecular sciences
|December 23, 2023
PubMed
概括

高胆固醇导致与年龄相关的听力损失,因为它会损害耳朵中的细胞清洁过程. 使用阿托瓦斯塔丁降低胆固醇可以通过恢复细胞功能来预防听力下降.

关键词:
与年龄有关的听力损失.自自是自的过程.听力损失 听力损失是什么溶酶体生物发生的生物发生.在 mTORC1 的情况下,mTORC1 是 mTORC1.转录因子的转录因子

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