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药物聚合物兼容性对晶体固体分散的湿度稳定性的影响机制

Chunhui Hu1, Qiuli Yan2, Yong Zhang2

  • 1State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810001, China.

Pharmaceuticals (Basel, Switzerland)
|December 23, 2023
PubMed
概括

湿度显著影响晶体固体分散 (CSD) 中的药物溶解和微观结构. 较高的聚合物兼容性通过减少分子流动性来提高药物稳定性,这对于一致的溶解行为至关重要.

关键词:
兼容性兼容性兼容性的兼容性晶体固体的分散性溶解行为是溶解行为.湿度稳定性 湿度稳定性微观结构的微观结构

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