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Updated: Jul 7, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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对LANCL2-ABA绑定模式的新见解,用于评估新的LANCL激动剂

Naomi Scarano1, Francesco Di Palma2, Nicola Origlia3

  • 1Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genova, Viale Benedetto XV, 3, 16132 Genoa, Italy.

Pharmaceutics
|December 23, 2023
PubMed
概括

兰氨酸合成酶C样蛋白2 (LANCL2) 激动剂,如酸 (ABA) 和AR-42,显示出治疗线粒体功能障碍的潜力. 这些化合物激活关键的细胞通路,为慢性和退行性疾病提供治疗可能性.

关键词:
AR-42 是一个AR-42.在BT-11中使用.在LANCL2中使用.阿布西斯酸是一种酸性酸.激进分子的激进分子.线粒体质子梯度的渐变.分子动力学分子动力学虚拟选 虚拟选 虚拟选

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