地中海饮食模式,结合能量和时间限制的饮食,改善了与超重个体间歇性禁食相比,素和奥门丁度的提高
Spyridon N Karras1, Theocharis Koufakis2, Djordje S Popovic3,4
1Division of Endocrinology and Metabolism, First Department of Internal Medicine, Medical School, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 St. Kiriakidi Street, 54636 Thessaloniki, Greece.
Nutrients
|December 23, 2023
概括
雅典东正教禁食 (AOF) 显著降低了瓦斯宾和增加了奥门丁水平,与其他时间限制饮食 (TRE) 方法不同. 这些adipokines的变化可能会影响心脏代谢健康.
科学领域:
- 代谢健康 代谢健康
- 营养科学 营养科学
- 内分泌学 在内分泌学.
背景情况:
- 雅典东正教禁食 (AOF) 结合了能量限制,时间限制饮食 (TRE) 和地中海饮食原则.
- 像瓦斯,奥门丁,内斯法和维斯法这样的阿迪波金在代谢调节中起作用.
- 了解不同饮食模式对阿迪波基因的影响对于代谢健康研究至关重要.
研究的目的:
- 为了比较AOF与16:8标准TRE疗法对特定阿迪波金水平的影响.
- 为了研究AOF诱导的血管和体内的变化的潜在心脏代谢影响.
- 为了确定与AOF相关的阿迪波金变异是否受到人类学或饮食因素的影响.
主要方法:
- 一项前性研究,涉及25名参与者练习AOF (12小时的进食窗口) 和12名对照者在16: 8 TRE.
- 在基线,第7周和第12周测量人体测量数据,饮食摄入量和血清阿迪波金水平 (瓦斯,奥门丁,内斯法丁,维斯法丁).
- 统计分析用于比较群体之间的变化,并评估对混变量的独立性.
主要成果:
- 在AOF组,瓦斯水平显著下降 (p=0.002),奥门丁水平显著增加 (p=0.001).
- 在16:8 TRE对照组中,没有观察到研究的阿迪波金的显著变化.
- 在AOF组的阿迪波金变异独立于年龄,性别,人体变化和脂肪摄入量.
结论:
- 雅典东正教的禁食显著改变了vaspin和omentin水平,与标准的16:8 TRE形成鲜明对比.
- 观察到的 vaspin 和 omentin 的变化可能会对代谢健康产生影响,特别是在像肥胖和2型糖尿病这样的疾病中.
- 需要进一步的研究来阐明AOF诱导的阿迪波金调节的精确心脏代谢效应.
相关概念视频
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