遗传多样性,进化动力学,和正在进行的Pedilanthus叶子卷曲病毒的传播
Zafar Iqbal1, Muhammad Shafiq2, Muhammad Naeem Sattar1
1Central Laboratories, King Faisal University, Al-Ahsa P.O. Box 55110, Saudi Arabia.
Viruses
|December 23, 2023
概括
佩迪兰修斯叶子卷曲病毒 (PeLCV) 显示出高度的遗传多样性和重组,表明其在巴基斯坦和印度的快速进化和扩张. 这种Begomovirus正在适应,其起源可追溯到1977年的巴基斯坦.
科学领域:
- 植物病毒学 植物病毒学
- 分子进化是分子进化的过程.
- 生物信息学是一种生物信息学.
背景情况:
- 佩迪兰修斯叶子卷曲病毒 (PeLCV) 是一种单一的贝戈病毒,在巴基斯坦和印度迅速蔓延,影响了许多植物物种.
- 病毒进化以快速的突变率为特征,导致显著的遗传多样性,影响生态和进化行为.
研究的目的:
- 在PeLCV基因组内计算地绘制序列变异动态,遗传异质性,区域多样性,系系和重组事件.
- 了解PeLCV的进化轨迹和多样化模式.
主要方法:
- 对52个全长PeLCV基因组序列的家族遗传学分析.
- 网络分析以确定进化关系和分类.
- 重组事件和人口选择的推断.
主要成果:
- 遗传学和网络分析揭示了7个主要分类,具有区域性,但不是宿主特定的划分.
- 1977年,PeLCV的起源被追溯到巴基斯坦的穆尔坦,随后蔓延到印度和巴基斯坦的其他地区.
- 在整个基因组中检测到高水平的物种间和物种内部重组.
- PeLCV群体表现出高遗传多样性 (π = 0.073%),高核酸替代率 (1.54 × 10−3) 和显著的重组.
结论:
- PeLCV表现出快速扩散和高度的遗传多样性,使其与其他贝戈莫病毒区别开来.
- 诸如高重组率和人口选择等因素有助于PeLCV的分歧和潜在适应新宿主.
- 这项研究提供了关于PeLCV.V.的出现和进化动态的见解.
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