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在一个74岁的男性呈现的缺食症下膜扩散大B细胞淋巴瘤:一个案例报告
Hisataka Ominato1,2, Yuki Komabayashi1, Shiori Suzuki1
1Department of Otolaryngology - Head and Neck Surgery, Sapporo Higashi Tokushukai Hospital, Sapporo, Hokkaido, Japan.
The American journal of case reports
|December 23, 2023
概括
恶性淋巴瘤是一种罕见的下喉瘤,可以导致呼吸道阻塞. 这一案例突显了通过化疗成功治疗的扩散性大B细胞淋巴瘤 (DLBCL),强调了更广泛的差异诊断的必要性.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 低喉瘤存在呼吸道阻塞的风险,需要及时诊断和治疗.
- 虽然状细胞癌是最常见的下喉恶性瘤,但存在其他罕见的瘤.
- 恶性下淋巴瘤异常罕见,记录病例有限,特征不明.
研究的目的:
- 报告一种罕见的在下垂体中扩散的大B细胞淋巴瘤 (DLBCL) 的病例.
- 突出下淋巴瘤的诊断和治疗方面的考虑.
- 贡献到关于下喉恶性淋巴瘤的有限现有文献.
主要方法:
- 一个案例研究74岁的男性呈现的消化不良和下喉瘤.
- 诊断程序包括内镜,计算机断层扫描 (CT),气管切除术和瘤活检.
- 进行了组织病理学和免疫组织化学分析 (CD20,CD3,CD10,Epstein-Barr病毒在位杂交).
主要成果:
- 内镜检查显示了一个光滑的,右下瘤;CT证实了40毫米的下质量.
- 组织病理学发现了扩散性大B细胞淋巴瘤 (DLBCL),对爱斯坦-巴尔病毒阴性.
- 免疫组织化学检测结果对CD20呈阳性,对CD3和CD10呈阴性.
- 患者接受了化疗,导致瘤大小减少和完全康复.
- 在为期两年的随访期间,没有观察到癌症复发.
结论:
- 低喉瘤,虽然通常是状细胞癌,但可以包括罕见的恶性瘤,如淋巴瘤.
- 这一案例强调了考虑在下喉群体中进行替代诊断的重要性.
- 需要进一步的病例报告和研究,以更好地了解下淋巴瘤的特征和治疗方法.
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