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部分切除术后局部癌患者的双边GFR之间的相关性
Wu Wensong1, Chang Fan2,3, Zhang Jianghui2,3
1Urology, The Third Central Clinical College of Tianjin Medical University, Tianjin, 300170, China.
International urology and nephrology
|December 23, 2023
概括
保护经过手术的脏.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
背景情况:
- 部分切除术 (PN) 是局部细胞癌 (RCC) 的标准治疗方法.
- 评估术后功能对于患者的治疗结果至关重要.
- 了解经过手术的脏和PN后的逆侧脏之间的相互作用至关重要.
研究的目的:
- 为了研究部分切除术 (PN) 后手术侧和逆侧的剩余膜过率 (GFR) 之间的关系.
- 为了识别局部细胞癌 (RCC) 的PN后术后功能预测因素.
主要方法:
- 对118名接受单边局部瘤 (T1-T2) 的PN患者的回顾性分析.
- 用SPECT/CT与99mTc-DTPA脏动态成像进行评估的淋巴细胞过率 (GFR).
- 线性回归分析以确定术后功能的独立预测因子.
主要成果:
- 经手术的术后GFR独立预测了对侧GFR (p=0.001).
- 瘤直径,年龄和相反的GFR预测了经过手术的脏GFR.
- 在手术一侧的GFR下降更大与相反侧的补偿能力较弱相关.
结论:
- 在PN期间保护经过手术的脏功能对于整体的脏保存至关重要.
- 经过手术的脏的积极结果有助于在手术后更好的逆侧功能.
- 在经过手术的脏中保持GFR是保持PN后整体功能的关键.
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