24小时霍尔特心电图在高甲状腺功能障碍症的正常和高甲状腺功能障碍患者中
1Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, Viale del Policlinico 155, 00161, Rome, Italy. jessica.pepe@uniroma1.it.
Journal of endocrinological investigation
|December 23, 2023
概括
常态血性原发性甲状腺功能障碍症 (PHPT) 患者没有表现出心律失常的增加. 然而,高血性PHPT患者患有更多的心律失常,可能是由于与高水平相关的QTc间隔较短.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 临床研究 临床研究
背景情况:
- 原发性副甲状腺炎症 (PHPT) 是一种涉及过量的副甲状腺激素的疾病.
- 与高血性PHPT相比,正常血性PHPT (NCPHPT) 的心脏影响尚不清楚.
研究的目的:
- 为了比较正常血性PHPT (NCPHPT) 患者与高血性PHPT患者和健康对照者的心律失常发生情况.
- 为了研究血清和副甲状腺激素 (PTH) 水平在心律失常中的作用.
主要方法:
- 一项比较研究涉及13名绝经后NCPHPT患者,13名高热血PHPT患者和13名年龄相匹配的对照.
- 所有参与者都接受了基础心电图,24小时霍尔特监测和矿物代谢的生物化学评估.
主要成果:
- 超血性PHPT患者的血清和PTH水平明显高于对照组和NCPHPT患者.
- 虽然QTc间隔在所有组中都是正常的,但在高热血症PHPT患者中,它明显较短.
- 与NCPHPT和对照组相比,高热血性PHPT患者的心律失常,包括超心室过早跳动 (SVPBs) 和心室过早跳动 (VPBs),在高热血性PHPT患者中明显更频繁.
结论:
- 与对照组相比,正常血性PHPT (NCPHPT) 患者没有出现心律失常的风险增加.
- 超血性PHPT与心律不整的发病率较高有关,可能与高血症引起的QTc间隔缩短有关.
关键词:
节律失常是因为失常.心血管疾病是什么心血管疾病荷尔特电脑电图 (ECG Holter) 是一种电子电图.过热血性原发性副甲状腺功能障碍症.常态血性原发性副甲状腺功能障碍症.甲状腺上腺激素激素的作用更多相关视频
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