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甲状腺切除术前后,在患有分化甲状腺癌的患者中,寿命质量的长度变化

Byung Hun Kim¹, Soo Rack Ryu², Jin Won Lee¹

¹Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul 04763, Republic of Korea.

The Journal of clinical endocrinology and metabolism

|December 23, 2023

概括

在分化甲状腺癌 (DTC) 患者的与健康相关的生活质量 (HR-QOL) 在甲状腺切除术后显著下降,但在5年内恢复并超过手术前水平. 遥控甲状腺切除术和避免RAI切除可以改善身体QOL.

科学领域:

在瘤学瘤学.
外科手术的结果
生活质量研究研究生命质量研究

背景情况:

差异化甲状腺癌 (DTC) 管理通常涉及甲状腺切除术.
评估甲状腺切除术对患者健康的长期影响至关重要.
与健康相关的生活质量 (HR-QOL) 是DTC存活率的一个关键结果指标.

研究的目的:

为了对DTC患者HR-QOL的纵向变化进行前性评估.
为了比较甲状腺切除术前和之后的多个时间点的HR-QOL.
确定影响甲状腺切除术后HR-QOL轨迹的因素.

主要方法:

185名接受甲状腺切除术的DTC患者的前性队列研究 (2013-2017).
使用UW-QOL和QOL-TV问卷进行手术前和手术后3,6,12,24,36和60个月的HR-QOL评估.
统计分析以确定QOL变化和影响因素.

主要成果:

甲状腺切除术后3个月HR-QOL得分下降,然后逐渐改善,超过了手术前水平5年.
整体甲状腺切除术,放射性 (RAI) 切除和副甲状腺功能障碍症与较低的身体QOL有关.
远程接入甲状腺切除术与对外观更高的满意度相关.
手术后心情和焦虑明显改善.

结论:

甲状腺切除术后的DTC患者经历了最初的HR-QOL下降,随后在5年内恢复和改善.
最少侵入性的方法 (遥控甲状腺切除术),较少的广泛的手术,以及避免RAI切除对身体QOL产生积极影响.
在整个DTC患者旅程中,解决情绪和焦虑是很重要的.

关键词:

有差异化的甲状腺癌.纵向前性研究是一种纵向前性研究.人们的生活质量.甲状腺切除术是指甲状腺切除术.

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