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具有增强抗癌活性的双重向化合物,通过微管破坏和素脱乙酶抑制增强抗癌活性

Yu-Wei Tseng1, Tsung-Jung Yang1, Yuan-Ling Hsu2

  • 1Department of Chemistry, National Taiwan University, Taipei, 106, Taiwan.

European journal of medicinal chemistry
|December 23, 2023
PubMed
概括

新的双重向抗癌药物结合了微管破坏和HDAC抑制. 这些纯氨酸-胺酸结合物对各种癌细胞具有强烈的细胞毒性,并且在没有毒性的小鼠中减少瘤生长.

关键词:
乳腺癌 乳腺癌 乳腺癌希斯蒂丁脱乙酶的使用亚酸酸盐的使用方法卡塔尼尼尼 在卡塔尼尼尼肺癌是一种肺癌.微管是微管中的一个.纯氨酸类型的结合物.

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