脑静脉血栓后头痛 - 患病率,机制和危险因素
Leonor Dias1, Maria João Pinto1, Rúben Maia2
1Neurology Department, Centro Hospitalar Universitário de São João, 4200-319, Porto, Portugal; Department of Clinical Neurosciences and Mental Health, Porto Medical Faculty (FMUP), 4200-319, Porto, Portugal.
概括
脑静脉血栓形成后的头痛 (PCH) 影响了近一半的患者,通常呈现为新的或现有的头痛类型. 患病前抑郁症是危险因素,而上部斜侧鼻血栓症可能是保护性的.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 血管神经学 血管神经学
背景情况:
- 头痛是脑静脉血栓形成 (CVT) 后的常见并发症.
- 在CVT后头痛 (PCH) 的潜在风险因素和病理生理学仍然不太清楚.
- 了解PCH对于有效的患者管理和随访至关重要.
研究的目的:
- 确定患有CVT的患者中PCH的患病率.
- 调查病理生理学,并确定与PCH相关的潜在风险因素.
- 描述患者在CVT后经历的头痛类型.
主要方法:
- 在2006年至2019年期间,对131名被诊断患有CVT的患者进行了回顾性观察性研究.
- PCH的诊断是基于随访预约期间的头痛报告.
- 通过随访MRI/MRV和PRIORITY-CVT分类来评估再通道化状态.
主要成果:
- 45.8%的患者在3个月的随访中报告了PCH.
- PCH包括先前存在的偏头痛/压力类型的头痛和新发性头痛 (压力类型,偏头痛,二次原因).
- 患病前抑郁症显著增加了PCH风险 (OR 7.9),而上斜鼻血栓症则降低了它 (OR 0.15).
结论:
- PCH是CVT的常见后续,有各种各样的头痛表现.
- 在没有先前头痛史的PCH患者中,必须排除头痛的次要原因.
- 病前抑郁症是PCH的重要危险因素,强调了CVT患者心理健康评估的重要性.
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