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创伤骨折的整形外科手术后手术部位感染的危险因素:一个嵌套的病例控制研究
T Sato1, K Shibahashi2, M Aoki3
1Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Sendai, Japan.
The Journal of hospital infection
|December 23, 2023
概括
在24小时内输血是骨科创伤手术后手术部位感染 (SSI) 的重要危险因素. 建议小心,以减轻这些患者的SSI风险.
科学领域:
- 整形外科手术 整形外科手术
- 传染病流行病学 传染病流行病学
- 创伤护理 创伤护理
背景情况:
- 手术部位感染 (SSI) 增加了医疗保健成本,降低了患者的生活质量.
- 确定可修改的SSI风险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 确定创伤相关骨折的骨科手术后SSI的特定可操作的风险因素.
- 为减少创伤患者SSI的预防策略提供信息.
主要方法:
- 一个嵌套的病例控制研究,利用日本创伤数据库 (JTDB) 全国注册.
- 倾向性得分匹配用于控制280家医院 (2004-2019) 的不可修改因素.
- 多层混合效应物流回归模型评估了SSI的风险因素.
主要成果:
- 分析包括15910名患者;377名 (2.4%) 患有SSI.
- 在24小时内输血是SSI的一个显著风险因素 (OR:1.51;95%CI:1.06-2.13).
- 其他潜在因素,如外部固定和门使用,显示趋势,但在本分析中没有统计学意义.
结论:
- 在骨科创伤手术后24小时内输血是SSI的一个关键可修改的风险因素.
- 临床实践应考虑策略,以尽量减少输血时间或减少SSI风险的必要性.
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